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Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI

StatusActive, Not Recruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 11 months later Jan 2027 → Jan 2028
See other at-risk trials from University of Pennsylvania

Record History

  1. Primary and study completion pushed from Jan 2027 to Jan 2028 Interventions: 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine (Drug) to 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine (Drug) · Eligibility criteria expanded, about 10 words · Study description revised Show 3 more changesShow less
    • Interventions: 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine (Drug) to 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine (Drug)
    • Eligibility criteria expanded, about 10 words
    • Study description revised
  2. Primary and study completion dates: Jan 2026 to Jan 2027 Trial status: Recruiting to Active, Not Recruiting · Site details revisedv9 Show 2 more changesShow less
    • Trial status: Recruiting to Active, Not Recruiting
    • Site details revised
  3. Primary completion date: Jan 2025 to Jan 2026v8
  4. Re-verified, no change to tracked fieldsv7
  5. Phase: Phase 2 to Not specifiedv6
Show 4 earlier versionsHide 4 earlier versions
  1. Phase: Not specified to Phase 2 Site contact updatedv5 Show 1 more changeShow less
    • Site contact updated
  2. Trial status: Active, Not Recruiting to Recruiting Eligibility criteria expanded, about 7 words · Study site revisedv4 Show 2 more changesShow less
    • Eligibility criteria expanded, about 7 words
    • Study site revised

    See this version in full on ClinicalTrials.gov ↗

  3. Trial status: Not Yet Recruiting to Active, Not Recruiting Study sites: 0 to 1 · Start date changed from estimate of Mar 2020 to Mar 11, 2020v3 Show 2 more changesShow less
    • Study sites: 0 to 1
    • Start date changed from estimate of Mar 2020 to Mar 11, 2020
  4. Phase: Phase 3 to Not specified Start date: Jan 2020 to Mar 2020v2 Show 1 more changeShow less
    • Start date: Jan 2020 to Mar 2020
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The investigators will conduct a tau PET scan in cognitively normal older adults and patients with Mild Cognitive Impairment (MCI), enrolled in the National Alzheimer's Coordinating Center (NACC) study at the University of Pennsylvania's Penn Memory Center/Alzheimer's Disease Core Center (PMC/ADC).
Trial Details
NCT Number NCT04251130
Lead Sponsor University of Pennsylvania
Collaborators: National Institutes of Health (NIH)
Conditions Mild Cognitive Impairment
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov