Clinical Trial

RH Genotype Matched RBC Transfusions

Study acronym: RBC
Recruiting Phase 1/2
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Summary
To determine the feasibility and efficacy of matching donor red cells by RH genotype for a cohort of chronically transfused patients with SCD.
Protocol Amendment History 11 amendments
This ClinicalTrials.gov record has been amended 11 times since 2019-11-06; most recent amendment 2026-04-24.
Status change: Not Yet Recruiting → Recruiting 2020-03-09
Trial Details
NCT Number NCT04156893
Lead Sponsor Children's Hospital of Philadelphia
Collaborators: New York Blood Center, National Heart, Lung, and Blood Institute (NHLBI)
Conditions Sickle Cells Disease
Enrollment 35 participants
Start Date 2020-01-30
Primary Completion 2029-04 (estimated)
Study Completion 2029-10 (estimated)
Updated on ClinicalTrials.gov 2026-04-27