Clinical Trial

Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

Name: Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) — clinical trial record (NCT04146051)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Active, Not Recruiting Phase 2

View on ClinicalTrials.gov →

Summary

This is a Phase IIb study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis

Protocol Amendment History 2 changes

notable Primary completion pushed: 2025-07-31 -> 2026-01-05 2026-08-15

minor Completion pushed: 2026-03-31 -> 2026-09-30 2026-08-15

Trial Details

NCT Number	NCT04146051
Lead Sponsor	Cartesian Therapeutics
Conditions	Myasthenia Gravis, Generalized
Enrollment	30 participants
Start Date	2019-12-04
Primary Completion	2026-01-05 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2026-08-14