| Detected | Trial | Change |
|---|---|---|
| 2026-08-15 | NCT04146051 Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) |
date change Primary completion pushed: 2025-07-31 -> 2026-01-05 |
| 2026-08-15 | NCT04146051 Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) |
date change Completion pushed: 2026-03-31 -> 2026-09-30 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06799247 | Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach… | Myasthaenia Gravis | Recruiting |
| Phase 2 | |||
| NCT07391605 | Descartes-08 in Autoantibody Myositis | Antisynthetase Syndrome | Recruiting |
| NCT06038474 | Descartes-08 for Patients With Systemic Lupus Erythematosus | Systemic Lupus Erythematosus (SLE) | Active, Not Recruiting |
| NCT04146051 | Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) | Myasthenia Gravis, Generalized | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT07089121 | Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders | Childhood-onset Systemic Lupus Erythematous | Recruiting |