Clinical Trial

Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer

Recruiting
View on ClinicalTrials.gov →
Summary
A randomized controlled clinical trial to compare the short and long term outcomes of transanal endoscopic microsurgery following radiotherapy or total mesorectal excision for the treatment of Rectal Cancer
Protocol Amendment History 6 changes
critical Recruitment opened 2026-07-29
critical Primary endpoint(s) modified 2026-07-29
notable Enrollment reduced: 300 -> 168 participants 2026-07-29
minor Trial arms changed: 3 -> 2 2026-07-29
notable Primary completion pushed: 2026-12 -> 2027-06-01 2026-07-29
minor Completion pushed: 2026-12 -> 2030-06-01 2026-07-29
Trial Details
NCT Number NCT04098471
Lead Sponsor The First Affiliated Hospital with Nanjing Medical University
Conditions Rectal Cancer
Enrollment 168 participants
Start Date 2021-10-01
Primary Completion 2027-06-01 (estimated)
Study Completion 2030-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-28