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DBS and Respiration

StatusUnknown
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated March 27, 2025 (before its estimated July 21, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Changed Registry marked status Unknown (sponsor has not verified the record since Mar 2024); last known: Recruiting
  2. Primary completion date: Jul 21, 2024 to Jul 21, 2026
    • Study completion date: Sep 21, 2024 to Sep 21, 2026
    v5
  3. Primary completion date: Jul 21, 2023 to Jul 21, 2024
    • Study completion date: Sep 21, 2023 to Sep 21, 2024
    v4
  4. Re-verified, no change to tracked fieldsv3
  5. Trial status: Not Yet Recruiting to Recruitingv2 Show 4 more changesShow less
    • Primary completion date: Jan 21, 2022 to Jul 21, 2023
    • Start date changed from estimate of Aug 21, 2019 to Apr 1, 2021
    • Study completion date: Feb 21, 2022 to Sep 21, 2023
    • Site details revised
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Patients referred to neurosurgery routinely and safely undergo deep brain stimulation (DBS) for treatment of neurological conditions, most commonly Parkinson's disease. The investigators have observed that respiratory problems (breathlessness) sometimes occur subsequent to DBS of the subthalamic nucleus (STN). This study aims to determine whether this is indeed a consequence of STN stimulation. Secondary objectives include identification of the respiratory physiological mediators of any interoceptive neuromodulation observed, changes in daily physical activity and MRI structural connectivity analysis.
Trial Details
NCT Number NCT04058457
Lead Sponsor University of Oxford
Collaborators: Oxford Brookes University
Conditions
(from sponsor)		 Parkinson Disease
Related terms Dyspnea, Movement Disorders, Parkinson Disease
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov