Clinical Trial

Oesophagectomy and Chest Wall and Respiratory Function

Terminated
View on ClinicalTrials.gov →
Why the trial stopped
Study closed before the planned recruitment target was reached because the study period ended before full recruitment could be completed. Recruitment ceased at study closure and data collection was completed for enrolled participants.
Summary
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery has been shown to reduce pulmonary infections by 20%. Enhanced recovery programmes are evidence-based protocols, developed to achieve early recovery after surgery with early mobilisation and chest physiotherapy and have been shown to reduce pulmonary complication rates as well. The investigators intend to objectively measure chest wall movement using 3D motion capture system as well as a wearable measurement system to monitor chest wall movement.
Protocol Amendment History 4 changes
critical Trial terminated 2026-07-24
notable Enrollment reduced: 100 -> 73 participants 2026-07-24
notable Primary completion moved earlier: 2025-08-31 -> 2024-08-31 2026-07-24
minor Completion moved earlier: 2025-08-31 -> 2024-08-31 2026-07-24
Trial Details
NCT Number NCT03835273
Lead Sponsor Imperial College London
Conditions Esophageal Cancer, Esophagectomy, Respiratory Function Loss
Enrollment 73 participants
Start Date 2019-05-29
Primary Completion 2024-08-31 (estimated)
Study Completion 2024-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-23