Cancer Driving Mutations in Endometriosis Lesions and Development of Progesterone Resistance

StatusActive, Not Recruiting
PhaseNot specified
Started

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Record History

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  1. Study completion pushed from Oct 1, 2026 to Oct 1, 2027
    • Eligibility criteria expanded, about 16 words
    • Secondary endpoints: details revised at 2 of 2 entries
  2. Re-verified, no change to tracked fieldsv17
  3. Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date changed from estimate of Oct 1, 2026 to Oct 1, 2024
    • Site details revised at 3 of 3 sites
    v16
  4. 4 versions Re-verified since Aug 4, 2021, no change to tracked fieldsv12-v15
  5. Trial status: Not Yet Recruiting to Recruiting
    • Primary and study completion dates: Sep 2026 to Oct 1, 2026
    • Start date changed from estimate of Sep 2020 to Oct 1, 2020
    • Site details revised at 3 of 3 sites
    v11
Show 9 earlier versionsHide 9 earlier versions
  1. Study sites: 1 to 3
    • Primary and study completion dates: Aug 2026 to Sep 2026
    • Start date: Aug 2020 to Sep 2020
    v10
  2. Start date: Jun 2020 to Aug 2020
    • Primary and study completion dates: Jun 2026 to Aug 2026
    v9
  3. Start date: Apr 2020 to Jun 2020
    • Primary and study completion dates: Apr 2026 to Jun 2026
    • Site contact updated
    v8
  4. Start date: Feb 2020 to Apr 2020
    • Primary and study completion dates: Feb 2026 to Apr 2026
    v7
  5. Start date: Dec 2019 to Feb 2020
    • Primary and study completion dates: Dec 2025 to Feb 2026
    • Collaborators: 1 to 2
    v6
  6. Primary and study completion dates: Nov 2025 to Dec 2025
    • Start date: Nov 2019 to Dec 2019
    v5
  7. Start date: Sep 2019 to Nov 2019
    • Primary and study completion dates: Sep 2025 to Nov 2025
    v4
  8. Start date: Jun 2019 to Sep 2019
    • Primary and study completion dates: Jun 15, 2025 to Sep 2025
    v3
  9. Start date: Apr 15, 2019 to Jun 2019
    • Primary completion date: Apr 15, 2025 to Jun 15, 2025
    • Study completion date: Dec 15, 2025 to Jun 15, 2025
    v2
  1. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will test the hypothesis that the molecular changes present in ectopic endometriosis lesions correlate with progesterone-resistant disease (using the criteria defined in this study) and are present in matched eutopic endometrium.
Trial Details
NCT Number NCT03756480
Lead Sponsor Johns Hopkins University
Collaborators: National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions
(from sponsor)		 Endometriosis, Endometrial Diseases
Related terms Endometriosis, Uterine Diseases
Enrollment 135 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov