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MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer

Name: MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer — clinical trial record (NCT03634267)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusTerminated

PhasePhase 1

SponsorM.D. Anderson Cancer Center

Started2018-08-03

View on ClinicalTrials.gov ↗

This trial studies how well magnetic resonance imaging (MRI)-guided internal radiation therapy (brachytherapy) works in treating participants with human papillomavirus (HPV) associated stage IB2-IV cervical or stage II-IVA vaginal cancer. Using MRI guidance during brachytherapy applicator placement may improve treatment planning in participants with cervical or vaginal cancer.

Amendment history 2 changes detected by DataLookout

2026-09-16

Trial terminated: PI Request

2026-09-16

Primary completion confirmed: August 2026 (last estimated December 2026)

Trial Details

NCT Number	NCT03634267
Lead Sponsor	M.D. Anderson Cancer Center Collaborators: National Cancer Institute (NCI)
Conditions	Human Papillomavirus-Related Carcinoma, Human Papillomavirus-Related Cervical Carcinoma, Stage IB2 Cervical Cancer AJCC v8, Stage II Cervical Cancer AJCC v8, Stage II Vaginal Cancer AJCC v8, Stage IIA Cervical Cancer AJCC v8, Stage IIA Vaginal Cancer AJCC v8, Stage IIA1 Cervical Cancer AJCC v8 +9 more
Enrollment	26 participants
Start Date	2018-08-03
Primary Completion	2026-08-26 (estimated)
Study Completion	2026-08-26 (estimated)
Updated on ClinicalTrials.gov	2026-09-15