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Maternal Grandmothers in the Born in Guangzhou Cohort Study

Study acronym: MGBIG
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 13 years later Dec 31, 2025 → Dec 31, 2038
See other at-risk trials from Guangzhou Women and Children's Medical Center

Record History

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  1. Primary completion pushed from Dec 31, 2025 to Dec 31, 2038 Show 6 more changesShow less
    • Lead sponsor: Guangzhou Women and Children's Medical Center to Guangzhou Women and Children's Medical Center
    • Secondary endpoints: details revised at 1 of 7 entries
    • Site details revised
    • Collaborators: details revised at 1 of 2 entries
    • Publications: details revised at 2 of 2 entries
    • Eligibility criteria expanded, about 4 words
  2. Re-verified, no change to tracked fieldsv6
  3. Primary completion date: Dec 31, 2023 to Dec 31, 2025v5
  4. Primary completion date: Apr 23, 2021 to Dec 31, 2023v4
  5. Re-verified, no change to tracked fieldsv3
  6. Lead sponsor: Xiu Qiu to Guangzhou Women and Children's Medical Centerv2
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.
Trial Details
NCT Number NCT03633162
Lead Sponsor Guangzhou Women and Children's Medical Center
Collaborators: Children's Hospital Medical Center, Cincinnati, University of Birmingham
Conditions
(from sponsor)		 Hereditary Transmission, Immune Development, Childhood Obesity, Host and Microbiome, Neurodevelopment
Related terms Pediatric Obesity
Enrollment 5,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov