Clinical Trial

Management of the PDA Trial

Study acronym: PDA
Active, Not Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
Estimate the risks and benefits of active treatment versus expectant management of a symptomatic patent ductus arteriosus (sPDA) in premature infants.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2018-02-28; most recent amendment 2026-04-20.
Status change: Recruiting → Active, Not Recruiting 2025-01-28
Status change: Active, Not Recruiting → Recruiting 2020-05-21
Status change: Recruiting → Active, Not Recruiting 2020-04-17
Status change: Not Yet Recruiting → Recruiting 2019-02-18
Trial Details
NCT Number NCT03456336
Lead Sponsor NICHD Neonatal Research Network
Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions Infant, Premature, Patent Ductus Arteriosus, Infant, Newborn, Diseases, Patent Ductus Arteriosus After Premature Birth
Enrollment 482 participants
Start Date 2019-02-22
Primary Completion 2025-03-02 (estimated)
Study Completion 2027-05-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-12