Clinical Trial

Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia

Active, Not Recruiting Phase 1/2
View on ClinicalTrials.gov →
Summary
This is a Phase I/II study designed to evaluate the kinetics of hematopoietic reconstitution and the incidence of acute chronic GVHD after partially matched related donor hematopoietic cell transplantation using an αβTCR/CD19+ cell depleted graft.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2018-02-09; most recent amendment 2026-03-30.
Status change: Recruiting → Active, Not Recruiting 2023-09-12
Trial Details
NCT Number NCT03431090
Lead Sponsor Nationwide Children's Hospital
Conditions Myelodysplasia, Hematologic Malignancy
Enrollment 20 participants
Start Date 2018-03-02
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-04-03