Clinical Trial

Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions

Recruiting Phase 4
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Summary
Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachycardia.
Protocol Amendment History 11 amendments
This ClinicalTrials.gov record has been amended 11 times since 2017-07-13; most recent amendment 2026-06-18.
Trial Details
NCT Number NCT03218137
Lead Sponsor Weill Medical College of Cornell University
Conditions Premature Ventricular Contraction (PVC)
Enrollment 100 participants
Start Date 2017-02-13
Primary Completion 2027-12-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-23