Clinical Trial

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Recruiting Phase 3
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Summary
This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors.
Protocol Amendment History 43 amendments
This ClinicalTrials.gov record has been amended 43 times since 2017-06-06; most recent amendment 2026-06-22.
Trial Details
NCT Number NCT03180268
Lead Sponsor NRG Oncology
Collaborators: National Cancer Institute (NCI)
Conditions Grade 2 Meningioma, Intracranial Meningioma
Enrollment 163 participants
Start Date 2017-09-12
Primary Completion 2027-06-15 (estimated)
Study Completion 2027-06-15 (estimated)
Updated on ClinicalTrials.gov 2026-06-25