Clinical Trial

Watch and Wait as Treatment for Patients With Rectal Cancer

Study acronym: WoW
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated November 7, 2023 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
A national cohort study with all patients scheduled for neoadjuvant treatment with (chemo)radiotherapy or short course radiotherapy with delayed surgery 6-8 weeks) for rectal cancer staged as cT4bNX/anycTanycN and cMRF+/anycTanycN and lateral lymph nodes on MRI (and patients that have been offered short course raditotherapy with delayed surgery due to various reasons). The tumours are positioned midrectal or low and are palpable with the finger. The patients offered this treatment after recommendations on their local multidisciplinary tumour board will be will be informed and offered to participate in the study. Patients scheduled for short course radiotherapy with immediate surgery cannot be included.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2017-04-21; most recent amendment 2023-11-03.
Status change: Active, Not Recruiting → Recruiting 2018-08-30
Trial Details
NCT Number NCT03125343
Lead Sponsor Sahlgrenska University Hospital
Collaborators: Karolinska Institutet
Conditions Rectal Neoplasms
Enrollment 400 participants
Start Date 2017-01
Primary Completion 2025-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2023-11-07