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Xenon-129 and Inert Fluorinated Gas Lung MRI: Study of Healthy Volunteers and Participants With Pulmonary Disease

StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Primary and study completion dates: Dec 31, 2025 to Dec 31, 2026
    • Study title shortened, about 2 words
    v10
  2. Primary and study completion dates: Dec 2023 to Dec 31, 2025v9 Show 4 more changesShow less
    • Interventions: Lung Clearance Index (Device), Magnetic Resonance Imaging (Device), Xenon-129 (Drug) to Lung Clearance Index (Device), Magnetic Resonance Imaging (Device), Xenon-129 and Perfluoropropane (19F) (Drug)
    • Eligibility criteria expanded, about 48 words
    • Study description expanded, about 334 words
    • Study title expanded, about 4 words
  3. Primary and study completion dates: Dec 2022 to Dec 2023v8
  4. Primary and study completion dates: Aug 2021 to Dec 2022v7
  5. Re-verified, no change to tracked fieldsv6
Show 4 earlier versionsHide 4 earlier versions
  1. Primary and study completion dates: Aug 2020 to Aug 2021v5
  2. Primary and study completion dates: Aug 2019 to Aug 2020v4
  3. Primary completion date: Dec 2016 to Aug 2019
    • Study completion date: Aug 2017 to Aug 2019
    v3
  4. Re-verified, no change to tracked fieldsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Aim of this study is to evaluate image quality and reproducibility of Xenon-129 and Inert fluorinated (19F) gas Magnetic Resonance Imaging (MRI) and to evaluate changes in lung structure and function in participants with cystic fibrosis (CF) and asthma compared to healthy controls.
Trial Details
NCT Number NCT02740868
Lead Sponsor The Hospital for Sick Children
Conditions
(from sponsor)		 Cystic Fibrosis, Asthma
Related terms Asthma, Cystic Fibrosis
Enrollment 30 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov