Clinical Trial

Sleep Apnea in Elderly

Recruiting Phase 4
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Record status
This record was last updated September 23, 2025 (before its estimated July 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
Sleep-disordered breathing (SDB or sleep apnea) is very common among elderly Veterans and leads to increased morbidity and mortality in this population. The proposal aims to identity whether oxygen, finasteride and acetazolamide can be effective in reducing unstable breathing and eliminating sleep apnea in the elderly via different mechanisms. This proposal will enhance the investigators' understanding of the pathways that contribute to the development of sleep apnea in the elderly. The investigators expect that the results obtained from this study will positively impact the health of Veterans by identifying new treatment modalities for sleep apnea. A cumulative effect of the investigators' research will fulfill the long-term goal of improving the quality of life of elderly Veterans suffering from sleep apnea and its potential life-threatening complications.
Protocol Amendment History 18 amendments
This ClinicalTrials.gov record has been amended 18 times since 2016-03-03; most recent amendment 2025-09-17.
Trial Details
NCT Number NCT02703220
Lead Sponsor VA Office of Research and Development
Conditions Sleep Apnea, Elderly Adults
Enrollment 100 participants
Start Date 2015-07-03
Primary Completion 2026-07-31 (estimated)
Study Completion 2026-07-31 (estimated)
Updated on ClinicalTrials.gov 2025-09-23