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NotablePrimary completion pushed from Jul 31, 2026 to Jul 30, 2027Completion pushed from Jul 31, 2026 to Dec 31, 2027 · Site contact updated · Eligibility criteria expanded, about 4 words · 1 morev20Show 4 more changesShow less
Completion pushed from Jul 31, 2026 to Dec 31, 2027
NotablePrimary and study completion dates: Jun 30, 2023 to Jun 30, 2024Site details revisedv16Show 1 more changeShow less
Site details revised
Show 14 earlier versionsHide 14 earlier versions
NotablePrimary and study completion dates: Dec 30, 2022 to Jun 30, 2023v15
NotablePrimary and study completion dates: Dec 31, 2021 to Dec 30, 2022v14
NotablePrimary and study completion dates: Dec 31, 2020 to Dec 31, 2021v13
NotablePrimary completion date: Jun 10, 2020 to Dec 31, 2020Completion date: Jul 10, 2020 to Dec 31, 2020v12Show 1 more changeShow less
Completion date: Jul 10, 2020 to Dec 31, 2020
NotablePrimary completion date: Dec 2, 2019 to Jun 10, 2020Completion date: Mar 31, 2020 to Jul 10, 2020 · Site contact updatedv11Show 2 more changesShow less
Completion date: Mar 31, 2020 to Jul 10, 2020
Site contact updated
MinorCompletion date: Dec 30, 2019 to Mar 31, 2020v10
MinorPrimary completion date: Jun 30, 2019 to Dec 2, 2019Completion date: Jun 30, 2019 to Dec 30, 2019v9Show 1 more changeShow less
Completion date: Jun 30, 2019 to Dec 30, 2019
MinorRe-verified, no change to tracked fieldsv8
MinorSite contact updatedv7
MinorEligibility criteria shortened, about 7 wordsStudy description expanded, about 11 wordsv6Show 1 more changeShow less
MinorPrimary and study completion dates: Jun 2019 to Jun 30, 2019Start date: Jul 2015 to Jul 3, 2015v4Show 1 more changeShow less
Start date: Jul 2015 to Jul 3, 2015
Minor2 versionsRe-verified since Aug 5, 2016, no change to tracked fieldsv2-v3
MinorStudy First Submitted
Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Sleep-disordered breathing (SDB or sleep apnea) is very common among elderly Veterans and leads to increased morbidity and mortality in this population. The proposal aims to identity whether oxygen, finasteride and acetazolamide can be effective in reducing unstable breathing and eliminating sleep apnea in the elderly via different mechanisms. This proposal will enhance the investigators' understanding of the pathways that contribute to the development of sleep apnea in the elderly. The investigators expect that the results obtained from this study will positively impact the health of Veterans by identifying new treatment modalities for sleep apnea. A cumulative effect of the investigators' research will fulfill the long-term goal of improving the quality of life of elderly Veterans suffering from sleep apnea and its potential life-threatening complications.