Aging, Geriatric Syndromes and Clonal Hematopoiesis

In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.

NCT Number	NCT02604563
Lead Sponsor	Washington University School of Medicine Collaborators: Edward P. Evans Foundation
Conditions	Geriatrics, Aged, Geriatric Syndromes, Cardiovascular Diseases
Enrollment	2,000 participants
Start Date	2016-03-10
Primary Completion	2030-04-30 (estimated)
Study Completion	2030-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-13