Clinical Trial

Efficacy of Amicar for Children Having Craniofacial Surgery

Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to determine whether Amicar (ε-aminocaproic acid) is effective in reducing blood loss in children undergoing craniofacial reconstruction surgery. The investigators hypothesize that Amicar will decrease intraoperative blood loss and decrease the need for perioperative blood product administration in children undergoing craniofacial surgery.
Protocol Amendment History 17 amendments
This ClinicalTrials.gov record has been amended 17 times since 2014-09-02; most recent amendment 2026-04-06.
Status change: Recruiting → Active, Not Recruiting 2018-04-12
Status change: Enrolling by Invitation → Recruiting 2015-08-21
Status change: Not Yet Recruiting → Enrolling by Invitation 2014-10-16
Trial Details
NCT Number NCT02229968
Lead Sponsor Children's National Research Institute
Conditions Craniosynostosis
Enrollment 22 participants
Start Date 2014-10
Primary Completion 2028-01 (estimated)
Study Completion 2028-03 (estimated)
Updated on ClinicalTrials.gov 2026-04-07