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NCT01644591 · ClinicalTrials.gov record · last posted 2026-08-20

Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases

StatusActive, Not Recruiting
PhasePhase 2
Started2012-08-02
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from the ClinicalTrials.gov record
This phase II trial studies how well stereotactic radiosurgery works in treating patients with melanoma that has spread to more than 3 places in the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue.

Protocol amendment history 2 changes detected by DataLookout

2026-08-21
critical
Primary completion pushed: 2026-08-31 → 2028-08-31
2026-08-21
minor
Completion pushed: 2026-08-31 → 2028-08-31
Trial Details
NCT Number NCT01644591
Lead Sponsor M.D. Anderson Cancer Center
Collaborators: National Cancer Institute (NCI)
Conditions Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC v8
Enrollment 49 participants
Start Date 2012-08-02
Primary Completion 2028-08-31 (estimated)
Study Completion 2028-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-20