Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department

StatusCompleted
PhasePhase 3
Started

Free. We email you which fields changed when ClinicalTrials.gov updates this record.

Track this trial
View on ClinicalTrials.gov ↗

Record History

  1. Trial status: Recruiting to Completed
    • Site details revised
    • Study arms: 0 to 2
    v6
  2. Re-verified, no change to tracked fieldsv5
  3. Primary completion date: Dec 2011 to Dec 2012
    • Study completion date: Dec 2011 to Dec 2013
    v4
  4. Primary and study completion dates: Dec 2008 to Dec 2011v3
  5. Primary completion date: Dec 2008
    • Secondary endpoints: details revised at 1 of 1 entry
    v2
  6. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Patients often come to the emergency department with bacterial skin infections (known as "cellulitis"). Some patients with very severe infections are admitted to hospital for antibiotic treatment and some are sent home on oral antibiotics. Many patients have moderate infections and are treated as outpatients with daily intravenous antibiotics for 2-5 days. In this patient group it is unclear if treatment with oral antibiotics is as effective as intravenous antibiotics. The purpose of this study is to determine if treatment of moderate cellulitis with an intravenous antibiotic (cefazolin) for 3-5 days is as effective as treatment with an oral antibiotic (moxifloxacin). We hypothesize that the oral agent will be as effective as intravenous treatment for moderate cellulitis.
Trial Details
NCT Number NCT00323219
Lead Sponsor University of British Columbia
Conditions
(from sponsor)		 Cellulitis
Related terms Cellulitis, Emergencies
Enrollment 390 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov