Clinical Trial

Radiation Therapy to Treat Musculoskeletal Tumors

Active, Not Recruiting Phase 2

Summary

Researchers at St. Jude Children's Research Hospital are looking for more effective ways to deliver radiation therapy to pediatric tumors of the bone and soft tissues. The goal of the study is to improve local control of musculoskeletal tumors with image-guided radiation therapy (IGRT) while minimizing radiation related side effects. IGRT uses computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) images to precisely define tumor location and to carefully plan radiation treatment. This approach allows doctors to deliver highly conformal radiation therapy to the tumor while protecting nearby healthy normal tissues.

Protocol Amendment History 41 amendments

This ClinicalTrials.gov record has been amended 41 times since 2005-09-12; most recent amendment 2026-02-18.

Status change: Recruiting → Active, Not Recruiting 2014-07-22

Trial Details

NCT Number	NCT00186992
Lead Sponsor	St. Jude Children's Research Hospital Collaborators: Lance Armstrong Foundation
Conditions	Sarcoma, Ewing's, Rhabdomyosarcoma, Soft Tissue Sarcoma, Musculoskeletal Tumors
Enrollment	202 participants
Start Date	2003-01-10
Primary Completion	2023-09-15 (estimated)
Study Completion	2029-10 (estimated)
Updated on ClinicalTrials.gov	2026-03-04