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MRS Measurement of Glutamate and GABA Metabolism in Brain

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

The 50 most recent of 396 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fields
  2. Re-verified, no change to tracked fields
  3. Re-verified, no change to tracked fields
  4. Eligibility criteria expanded, about 16 words
    • Study description revised
  5. Re-verified, no change to tracked fieldsv392
Show 45 earlier versionsHide 45 earlier versions
  1. Study Status, Study Description, Eligibilityv391
  2. 44 versions Re-verified since Mar 14, 2025, no change to tracked fieldsv347-v390
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will use magnetic resonance spectroscopy (MRS) to measure in the brain the transfer of \[13\]C as it is naturally metabolized from glucose to specific chemical transmitters. From this method, we can measure the rate of production of an important excitatory neurotransmitter (glutamate) as well as an inhibitory neurotransmitter (GABA).
Trial Details
NCT Number NCT00109174
Lead Sponsor National Institute of Mental Health (NIMH)
Conditions
(from sponsor)		 Normal Physiology
Enrollment 200 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov