Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

StatusRecruiting
PhaseNot specified
Started

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Record History

The 50 most recent of 389 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fields
  2. Re-verified, no change to tracked fields
  3. Eligibility criteria expanded, about 1 word
    • Study description shortened, about 4 words
  4. 28 versions Re-verified since Nov 27, 2025, no change to tracked fieldsv359-v386
  5. Study description expanded, about 6 words
    • Eligibility criteria expanded, about 2 words
    v358
Show 18 earlier versionsHide 18 earlier versions
  1. 4 versions Re-verified since Jul 31, 2025, no change to tracked fieldsv354-v357
  2. Eligibility criteria revised
    • Study description shortened, about 2 words
    v353
  3. 8 versions Re-verified since Apr 30, 2025, no change to tracked fieldsv345-v352
  4. Study Status, Study Description, Eligibilityv344
  5. 4 versions Re-verified since Dec 20, 2024, no change to tracked fieldsv340-v343
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, severe temper tantrums). Researchers will describe the moods and behaviors of children with these symptoms and use specialized testing and brain imaging to learn about the brain changes associated with this disorder.
Trial Details
NCT Number NCT00025935
Lead Sponsor National Institute of Mental Health (NIMH)
Conditions
(from sponsor)		 Mood Disorder
Related terms Behavior, Conduct Disorder, Mood Disorders
Enrollment 2,350 participants
Start Date
Updated on ClinicalTrials.gov