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Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers

StatusCompleted
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Amendment history

The 50 most recent of 352 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Minor

    Eligibility criteria expanded, about 1 word

    Publications: details revised at 8 of 8 entries

    Show what changed: Eligibility criteria
    * INCLUSION CRITERIA: CONTROLS: No psychiatric or severe chron [...]

  2. Minor

    47 amendments

    47 re-verifications since 2025-02-20, no change to tracked fields

    v305-v351

  3. Minor

    Trial status: Recruiting to Completed

    Enrollment target: estimated 3420 to confirmed 3273; Site details revised

    Study Status, Study Design, Contacts/Locations, Referencesv304

  4. Minor

    Study Status, Study Description

    Re-verified, no change to tracked fields

    v303

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this study is to use brain imaging technology to compare differences in brain structure, chemistry, and functioning in individuals with brain and mental disorders compared to healthy volunteers. Schizophrenia is a brain disorder that results from subtle changes and abnormalities in neurons. These deficits likely occur in localized regions of the brain and may result in widespread, devastating consequences. The neuronal abnormalities are inherited through a complex combination of genetic and environmental factors. Brain imaging technologies can be used to better characterize brain changes in individuals with schizophrenia. This study will use magnetic resonance imaging (MRI) scans to identify predictable, quantifiable abnormalities in neurophysiology, neurochemistry and neuroanatomy that characterize schizophrenia and other neurological and neuropsychiatric disorders....
Trial Details
NCT Number NCT00004571
Lead Sponsor National Institute of Mental Health (NIMH)
Conditions Schizophrenia, Normal Physiology
Enrollment 3,273 participants
Start Date
Updated on ClinicalTrials.gov