Sponsor Pipeline

argenx Clinical Trial Pipeline

Data updated daily from ClinicalTrials.gov — last refresh 2026-08-16
42
Active Trials
23
Recruiting
17
Phase 3
4
Disease Areas
18
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-08-14 NCT07610564
A Study to Assess the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults…
Recruitment opened
2026-08-14 NCT07610564
A Study to Assess the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults…
Trial sites expanded: 0 -> 3 locations
2026-08-13 NCT07570316
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants…
Trial sites expanded: 18 -> 22 locations
2026-08-11 NCT06298552
A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With…
date change Completion pushed: 2027-06 -> 2028-06
2026-08-11 NCT07287982
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and…
Trial sites expanded: 17 -> 24 locations
2026-07-31 NCT07284420
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to…
Trial sites expanded: 15 -> 24 locations
2026-07-31 NCT07294170
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy…
Trial arms changed: 1 -> 2
2026-07-31 NCT07294170
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy…
Trial sites expanded: 18 -> 29 locations
2026-07-25 NCT07673627
ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of…
Recruitment opened
2026-07-25 NCT06436742
A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants…
overall status: Recruiting → Active, Not Recruiting
2026-07-25 NCT05523167
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult…
Trial completed
2026-07-25 NCT05523167
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult…
Primary endpoint(s) modified
2026-07-25 NCT05523167
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult…
date change Primary completion moved earlier: 2026-12-01 -> 2026-07-02
2026-07-25 NCT05523167
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult…
date change Completion moved earlier: 2027-02-01 -> 2026-07-02
2026-07-23 NCT07091630
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
Trial sites expanded: 61 -> 71 locations
2026-07-22 NCT06920004
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
Trial sites expanded: 75 -> 82 locations
2026-07-21 NCT07583641
A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune…
date change Primary completion moved earlier: 2030-12-04 -> 2029-01-20
2026-07-21 NCT07583641
A Study to Learn About How Well the Medicine Efgartigimod Works to Treat Autoimmune…
date change Completion moved earlier: 2031-07-26 -> 2029-05-12
New Trial Filings, Last 30 Days
First PostedTrialPhaseStatus
2026-08-12 NCT07760818 A Study to Assess Efficacy and Safety of Efgartigimod in Adults With Sjogren's… Phase 2 Not Yet Recruiting
2026-08-04 NCT07746089 A Study to Assess Efficacy and Safety of Adimanebart in Adult and Pediatric Participants… Phase 3 Not Yet Recruiting
Active Trials by Phase
Phase 4
1
Phase 3
12
Phase 2/3
5
Phase 2
12
Phase 1
5
Not specified
7
Active Trials — top 25 of 42
NCT IDTitleConditionStatus
Phase 4
NCT06909214 A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With… New Onset Generalized Myasthenia Gravis (gMG) Recruiting
Phase 3
NCT06544499 A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With… Primary Immune Thrombocytopenia (ITP) Recruiting
NCT07596849 A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants… Graves Disease Recruiting
NCT06920004 A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP Chronic Inflammatory Demyelinating Polyneuropathy Recruiting
NCT07091630 A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP Chronic Inflammatory Demyelinating Polyneuropathy Recruiting
NCT07570316 A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants… Graves' Disease Recruiting
NCT04812925 A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in… Primary Immune Thrombocytopenia Active, Not Recruiting
NCT06684847 A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's… Primary Sjogrens Disease Active, Not Recruiting
NCT06742190 A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With… Multifocal Motor Neuropathy (MMN) Active, Not Recruiting
NCT06558279 A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular… Myasthenia Gravis, Ocular Active, Not Recruiting
NCT05979441 A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of… Myositis Enrolling by Invitation
NCT07746089 A Study to Assess Efficacy and Safety of Adimanebart in Adult and Pediatric Participants… Congenital Myasthenic Syndrome Not Yet Recruiting
NCT06298552 A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With… Generalized Myasthenia Gravis Active, Not Recruiting
Phase 2/3
NCT04833894 Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod… Generalized Myasthenia Gravis Recruiting
NCT06392386 A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With… Generalized Myasthenia Gravis Recruiting
NCT07194850 A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age… Immune Thrombocytopenia (ITP) Recruiting
NCT05374590 Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod… Generalized Myasthenia Gravis Enrolling by Invitation
NCT07638566 A Study to Assess the Correct Dose, Safety and Efficacy of Empasiprubart in Adolescent… Chronic Inflammatory Demyelinating Polyradiculoneuropathy Not Yet Recruiting
Phase 2
NCT06655155 A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic… Systemic Sclerosis (SSc) Recruiting
NCT07673627 ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of… AChR-Ab Seropositive Generalized Myasthenia Gravis Recruiting
NCT07284420 ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to… AChR-Ab Seropositive Generalized Myasthenia Gravis Recruiting
NCT07287982 A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and… Spinal Muscular Atrophy (SMA) Recruiting
NCT04280718 A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of… Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Active, Not Recruiting
NCT06284954 A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis Dermatomyositis Active, Not Recruiting
NCT05405361 A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy… Multifocal Motor Neuropathy (MMN) Active, Not Recruiting
See all 42 active argenx trials with filters →
Disease Areas
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