Sponsor pipeline

Centessa Pharmaceuticals (UK) Limited clinical trial pipeline

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

1 trial changed in the last 30 days: 0 stopped, 0 with notable changes, 1 with a minor change only.

Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.

NCT ID	Title	Condition	Status	Updated
Phase 2/3
NCT07598708	A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the…	Narcolepsy Type 1	Recruiting	2026-10-02
Phase 2
NCT06752668	A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia	Narcolepsy Type 1	Recruiting	2026-04-27
NCT07096674	A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic…	Narcolepsy Type 1	Recruiting	2026-04-16
Phase 1
NCT07413666	A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years	Healthy Adult Male and Female Volunteers	Recruiting	2026-02-25
NCT07082829	A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age	Excessive Daytime Sleepiness	Recruiting	2025-12-24

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