Drug Pipeline

Telaglenastat Hydrochloride Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
5
Active Studies
0
Recruiting
1
Top Sponsors
9
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-28 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Primary completion pushed: 2023-11-08 -> 2026-09-11
2026-05-28 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Completion pushed: 2023-11-08 -> 2026-09-11
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
Trial terminated
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
critical why stopped: null → "Other - Drug supply issues and withdrawal of company support."
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
Enrollment reduced: 36 -> 19 participants
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Primary completion moved earlier: 2026-06-30 -> 2023-11-08
2026-05-14 NCT03798678
CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With…
date change Completion moved earlier: 2026-06-30 -> 2023-11-08
2026-05-14 NCT03528642
Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With…
date change Primary completion pushed: 2026-05-08 -> 2026-09-11
2026-05-14 NCT03528642
Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With…
date change Completion pushed: 2026-05-08 -> 2026-09-11
Active Studies by Phase
Phase 2
1
Phase 1/2
1
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT03872427 Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor… Advanced Malignant Solid Neoplasm Active, Not Recruiting
Phase 1/2
NCT03831932 Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage… Advanced Lung Non-Small Cell Carcinoma Active, Not Recruiting
Phase 1
NCT03528642 Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With… Astrocytoma, IDH-Mutant, Grade 2 Active, Not Recruiting
NCT04250545 Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in… Leptomeningeal Neoplasm Active, Not Recruiting
NCT03798678 CB-839 HCl in Combination With Carfilzomib and Dexamethasone in Treating Patients With… Recurrent Multiple Myeloma Active, Not Recruiting
Sponsors Running Telaglenastat Hydrochloride Trials
Disease Areas
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