| Detected | Trial | Change |
|---|---|---|
| 2026-06-09 | NCT06619236 Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in… |
Enrollment increased: 448 -> 530 participants |
| 2026-06-03 | NCT07166094 Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's… |
Trial sites expanded: 74 -> 81 locations |
| 2026-06-03 | NCT07225270 Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to… |
Trial sites expanded: 10 -> 13 locations |
| 2026-06-03 | NCT07288177 Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell… |
Trial sites expanded: 15 -> 22 locations |
| 2026-05-28 | NCT06619236 Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in… |
Enrollment reduced: 530 -> 448 participants |
| 2026-05-27 | NCT05579366 Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/… |
Primary endpoint(s) modified |
| 2026-05-27 | NCT05579366 Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/… |
Enrollment increased: 764 -> 884 participants |
| First Posted | Trial | Phase | Status |
|---|---|---|---|
| 2026-05-22 | NCT07604766 An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of… | Phase 3 | Not Yet Recruiting |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT07166094 | Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's… | Endometrial Cancer | Recruiting |
| NCT07225270 | Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to… | Ovarian Cancer | Recruiting |
| NCT07604766 | An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of… | Platinum-resistant Ovarian Cancer | Not Yet Recruiting |
| NCT07564141 | Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to… | Platinum-Sensitive Ovarian Cancer | Not Yet Recruiting |
| NCT06619236 | Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in… | Platinum-resistant Ovarian Cancer | Active, Not Recruiting |
| Phase 2 | |||
| NCT07288177 | Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell… | Non-small Cell Lung Cancer (NSCLC) | Recruiting |
| NCT07539311 | Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced… | Gastrointestinal Cancers | Recruiting |
| Phase 1/2 | |||
| NCT05579366 | Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/… | High Grade Epithelial Ovarian Cancer | Recruiting |