Drug Pipeline

R-DXd Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
7
Active Studies
4
Recruiting
1
Phase 3
2
Top Sponsors
5
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-28 NCT04938817
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-27 NCT06843447
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)
Trial sites expanded: 17 -> 20 locations
2026-05-23 NCT06161025
A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade…
Trial sites expanded: 129 -> 146 locations
2026-05-14 NCT06843447
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)
Enrollment increased: 280 -> 460 participants
2026-05-14 NCT06843447
A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)
Trial arms changed: 7 -> 10
Active Studies by Phase
Phase 2/3
1
Phase 2
4
Phase 1/2
2
Active Trials
NCT IDTitleConditionStatus
Phase 2/3
NCT06161025 A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade… Solid Cancer Recruiting
Phase 2
NCT06780085 A Study of Investigational Agents in Participants With Previously Treated Stage IV… Carcinoma, Non-Small-Cell Lung Recruiting
NCT06780098 Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated… Lung Neoplasm Recruiting
NCT06864169 A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers… Gastrointestinal Cancer Active, Not Recruiting
NCT06660654 A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors… Advanced Solid Tumor Active, Not Recruiting
Phase 1/2
NCT06843447 A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003) Ovarian Cancer Recurrent Recruiting
NCT04938817 Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With… Small Cell Lung Carcinoma Active, Not Recruiting
Sponsors Running R-DXd Trials
Disease Areas
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