Drug Pipeline

Nirogacestat Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
10
Active Studies
3
Recruiting
8
Top Sponsors
1
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-06-06 NCT04722146
A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple…
date change Primary completion moved earlier: 2027-04-07 -> 2025-10-13
Active Studies by Phase
Phase 4
1
Phase 2
4
Phase 1/2
2
Phase 1
3
Active Trials
NCT IDTitleConditionStatus
Phase 4
NCT07176689 Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) Desmoid Tumor Recruiting
Phase 2
NCT05879146 Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical… Tumor Recruiting
NCT04195399 A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed… Desmoid Fibromatosis Active, Not Recruiting
NCT07170644 A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis… Desmoid Tumor Active, Not Recruiting
NCT07539454 Nirogacestat in Patients With Kaposi Sarcoma AIDS-Related Kaposi Sarcoma Not Yet Recruiting
Phase 1/2
NCT04126200 Platform Study of Belantamab Mafodotin as Monotherapy and in Combination With Anti-cancer… Multiple Myeloma Active, Not Recruiting
NCT07084896 Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in… Multiple Myeloma Active, Not Recruiting
Phase 1
NCT05137054 A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other… Multiple Myeloma Recruiting
NCT05556798 A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in… Multiple Myeloma Active, Not Recruiting
NCT04722146 A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple… Multiple Myeloma Active, Not Recruiting
Sponsors Running Nirogacestat Trials
Disease Areas
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