| Detected | Trial | Change |
|---|---|---|
| 2026-06-12 | NCT07118215 A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine… |
date change Primary completion pushed: 2026-04-05 -> 2026-06-25 |
| 2026-06-12 | NCT07118215 A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine… |
date change Completion pushed: 2026-04-05 -> 2026-06-25 |
| 2026-06-05 | NCT06951711 A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… |
Trial sites expanded: 74 -> 78 locations |
| 2026-06-03 | NCT05980949 Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in… |
Trial sites expanded: 421 -> 426 locations |
| 2026-05-23 | NCT06937229 A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in… |
Trial sites expanded: 243 -> 253 locations |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 3 | |||
| NCT06951698 | A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… | Bipolar-I Disorder With Mania or Mania With Mixed Features | Recruiting |
| NCT05511363 | A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… | Psychosis Associated With Alzheimer's Disease | Recruiting |
| NCT07424404 | A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the… | Schizophrenia | Recruiting |
| NCT06882785 | A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult… | Schizophrenia | Recruiting |
| NCT06976216 | A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment… | Alzheimer's Disease | Recruiting |
| NCT05980949 | Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in… | Psychosis Associated With Alzheimer's Disease | Recruiting |
| NCT06126224 | A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated… | Psychosis Associated With Alzheimer's Disease | Recruiting |
| NCT06929273 | A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in… | Bipolar Disorder Type I With Mania | Recruiting |
| NCT06937229 | A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in… | Alzheimer Disease | Recruiting |
| NCT06947941 | A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis… | Alzheimer Disease | Recruiting |
| NCT07288567 | A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia… | Schizophrenia | Recruiting |
| NCT06951711 | A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes… | Bipolar Disorder Type I With Mania or Mania With Mixed Features | Recruiting |
| NCT06976203 | A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment… | Alzheimer's Disease | Recruiting |
| NCT06585787 | A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's… | Alzheimer Disease | Recruiting |
| NCT07284745 | A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With… | Irritability Associated With Autism Spectrum Disorder | Not Yet Recruiting |
| NCT07285798 | A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With… | Irritability Associated With Autism Spectrum Disorder | Not Yet Recruiting |
| Phase 1 | |||
| NCT07118215 | A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine… | Healthy Volunteers | Recruiting |
| Not specified | |||
| NCT07571148 | Real-world Patient Characteristics, Treatment Patterns, and Healthcare Utilization Among… | Schizophrenia | Active, Not Recruiting |