| Detected | Trial | Change |
|---|---|---|
| 2026-06-02 | NCT06360354 A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-06-02 | NCT06360354 A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With… |
Enrollment reduced: 350 -> 120 participants |
| 2026-06-02 | NCT06360354 A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With… |
date change Primary completion moved earlier: 2027-02-26 -> 2026-10-31 |
| 2026-06-02 | NCT06360354 A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With… |
date change Completion moved earlier: 2029-02-25 -> 2026-11-30 |
| 2026-05-29 | NCT06593522 A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-29 | NCT06593522 A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC… |
Enrollment reduced: 200 -> 61 participants |
| 2026-05-29 | NCT06593522 A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC… |
date change Primary completion moved earlier: 2028-11-29 -> 2026-10-31 |
| 2026-05-29 | NCT06593522 A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC… |
date change Completion moved earlier: 2030-11-29 -> 2026-11-30 |
| 2026-05-29 | NCT06333951 Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced… |
overall status: "Recruiting" → "Active Not Recruiting" |
| 2026-05-29 | NCT06333951 Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced… |
Enrollment reduced: 500 -> 49 participants |
| 2026-05-29 | NCT06333951 Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced… |
date change Primary completion moved earlier: 2028-10-27 -> 2026-10-31 |
| 2026-05-29 | NCT06333951 Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced… |
date change Completion moved earlier: 2031-10-27 -> 2026-11-30 |
| 2026-05-29 | NCT05094336 A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY… |
date change Primary completion pushed: 2026-05-27 -> 2026-11-30 |
| 2026-05-29 | NCT05094336 A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY… |
date change Completion moved earlier: 2028-05-29 -> 2026-11-30 |
| NCT ID | Title | Condition | Status |
|---|---|---|---|
| Phase 2 | |||
| NCT06593522 | A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC… | MTAP-deleted NSCLC | Active, Not Recruiting |
| Phase 1/2 | |||
| NCT05094336 | A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY… | Advanced MTAP-null Solid Tumors | Active, Not Recruiting |
| Phase 1 | |||
| NCT06333951 | Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced… | Thoracic Tumors | Active, Not Recruiting |
| NCT06360354 | A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With… | Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers | Active, Not Recruiting |