Disease landscape

Ankylosing Spondylitis clinical trials

Get alerts when Ankylosing Spondylitis trials change

130 active trials 66 recruiting 12 Phase 3 98 sponsors 25 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-02

What changed in the last 30 days

2026-09-19
Primary completion pushed: 2027-05-03 → 2027-12-31
Completion pushed: 2027-05-03 → 2027-12-31
NCT06888193 A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers… · UCB Biopharma SRL · Phase 1
2026-09-16
Primary completion pushed: 2027-09-01 → 2028-08-01
Enrollment closed, study ongoing
Completion pushed: 2027-09-01 → 2028-08-01
NCT06299917 WORK-ON Vocational Rehabilitation for People With Inflammatory Arthritis · The Danish Center for Expertise in Rheumatology
2026-09-19
Primary endpoint(s) modified
NCT07047703 EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1) · Grey Wolf Therapeutics · Phase 1/2
2026-09-17
Primary endpoint(s) modified
Interventions modified
Primary completion moved earlier: 2028-06-30 → 2028-04-30
Completion moved earlier: 2029-06-30 → 2028-06-30
NCT07578220 A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis · China-Japan Friendship Hospital
2026-09-23
Trial completed
Primary completion confirmed: June 2025 (last estimated May 2026)
NCT05861102 Efficacy and Safety Study of Jaktinib in Subjects With Active Ankylosing Spondylitis(AS) · Suzhou Zelgen Biopharmaceuticals Co.,Ltd · Phase 3
2026-09-09
Trial completed
NCT04436640 A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in… · UCB Biopharma SRL · Phase 3
2026-09-16
Trial completed
Final enrollment: 238 participants (planned 300)
Primary completion confirmed: September 2026 (last estimated January 2027)
NCT06587828 A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in… · TScan Therapeutics, Inc.
2026-09-16
Trial completed
Study completion confirmed: March 2026 (last estimated May 2026)
NCT07414823 Walking Football for Axial Spondyloarthritis · Portsmouth Hospitals NHS Trust
2026-09-19
Trial completed
Final enrollment: 21 participants (planned 24)
Study completion confirmed: September 2025 (last estimated November 2025)
NCT06823726 Taekwondo for Axial Spondyloarthritis · Wonju Severance Christian Hospital
2026-09-12
Enrollment closed, study ongoing
NCT06583980 INSELMA - a Randomised Controlled Trial · The Danish Center for Expertise in Rheumatology
2026-09-06
Trial status changed: Recruiting → Unknown
NCT05835518 An Observational, Prospective Study to Assess the Efficacy and Safety of Adalloce in… · Yuhan Corporation
2026-09-06
Trial status changed: Recruiting → Unknown
NCT06577350 Osteosarcopenia in Axial Spondyloarthritis · Ankara University
2026-09-06
Trial status changed: Recruiting → Unknown
NCT06544343 Integration of Remote Monitoring in the Management of Chronic Immunosuppressive Therapy · University Of Perugia

New sponsor entrants, last 90 days sponsors with their first trial in this area

First postedTrialSponsorPhase
2026-09-29 NCT07847320 Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an… Diakonie-Klinikum Stuttgart new
2026-09-29 NCT07847879 Effects of Pulmonary Rehabilitation Exercises in Patients With Axial Spondyloarthritis Sisli Hamidiye Etfal Training and Research Hospital new
2026-09-23 NCT07836374 RENEW Intervention for Axial Spondyloarthritis University of Michigan new
2026-09-23 NCT07836283 Evaluation of the Efficacy and Safety of Bimekizumab (BZK) or Adalimumab (ADA) in the… University Hospital, Rouen new Phase 3
2026-09-22 NCT07833033 Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis Izmir University of Economics new
2026-09-22 NCT07834788 Lacticaseibacillus Rhamnosus GG Supplementation in Active Ankylosing Spondylitis Acibadem University new
2026-09-16 NCT07821541 Changes in Serum Calprotectin and Their Clinical Correlates in Axial Spondyloarthritis… Giresun University new
2026-08-20 NCT07776652 Postural Biofeedback and Exercise in Axial Spondyloarthritis Istanbul University - Cerrahpasa new
2026-08-18 NCT07770646 A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor… The University of Texas Health Science Center, Houston new Phase 4
2026-07-07 NCT07688174 The REFLECT Study- Flares in axSpA Royal United Hospitals Bath NHS Foundation Trust new

Active trials by phase

Phase 1
4
Phase 1/2
3
Phase 2
7
Phase 2/3
3
Phase 3
9
Phase 4
12
Not charted: 92 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 130

NCT IDTitleSponsorStatusUpdated
Phase 4
NCT07087912 Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in… University of Sao Paulo General Hospital Recruiting 2026-07-20
NCT06454188 A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients… CARE ARTHRITIS LTD. Recruiting 2026-04-03
NCT05303285 A Study Evaluating the Efficacy of Secukinumab 300mg in Chinese Adults With Active… Tongji Hospital Recruiting 2026-01-27
NCT07160231 REDO-JAK: Dose Reduction of Janus Kinase Inhibitors in Patients With Inflammatory… Sint Maartenskliniek Recruiting 2025-09-17
NCT06707194 Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis Nanfang Hospital, Southern Medical University Recruiting 2025-06-26
NCT06112665 ToFAcitinib in Early Active Axial SpondyloarThritis: Charite University, Berlin, Germany Recruiting 2024-11-26
NCT07770646 A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor… The University of Texas Health Science Center, Houston Not Yet Recruiting 2026-09-09
NCT05622708 A Study of Secukinumab to Evaluate Maintenance of Response in Participants With… Novartis Pharmaceuticals Active, Not Recruiting 2026-08-21
NCT07582146 Effectiveness and Safety of Acemetacin in Active Axial Spondyloarthritis: A Real-world… Chinese PLA General Hospital Not Yet Recruiting 2026-05-12
NCT05879419 Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases University of Sao Paulo General Hospital Active, Not Recruiting 2026-05-04
NCT07018206 Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients… CARE ARTHRITIS LTD. Not Yet Recruiting 2026-02-06
NCT06833112 Interleukin-17 (IL-17) Inhibitor in Combination With Tumor Necrosis Factor α (TNFα… The Affiliated Hospital Of Guizhou Medical University Not Yet Recruiting 2025-02-18
Phase 3
NCT07172360 Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active… Jiangsu vcare pharmaceutical technology co., LTD Recruiting 2026-01-02
NCT07261644 A Study to Evaluate the Efficacy and Safety of 608 in Adult Subjects With Active… Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. Recruiting 2025-12-10
NCT07237568 A Study to Evaluate Efficacy and Safety of LNK01001 in Adults With Ankylosing Spondylitis Lynk Pharmaceuticals Co., Ltd Recruiting 2025-11-20
NCT06860750 A Trial of SHR-1314 Injection in Adult Patients With Active Non-radiographic Axial… Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting 2025-06-22
NCT06000956 A Study of Comparing Overall Improvement of Patients With Spondyloarthritis Treated With… Tasly Pharmaceutical Group Co., Ltd Recruiting 2024-11-21
NCT07836283 Evaluation of the Efficacy and Safety of Bimekizumab (BZK) or Adalimumab (ADA) in the… University Hospital, Rouen Not Yet Recruiting 2026-09-23
NCT07349329 A Study to Evaluate the Efficacy and Safty of 608 in Patients With Non- Radiographic… Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. Not Yet Recruiting 2026-01-16
NCT05785611 A Study Evaluating the Effect of Filgotinib in Participants With Active Axial… Alfasigma S.p.A. Active, Not Recruiting 2025-12-04
NCT06333210 Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in… Biocad Active, Not Recruiting 2024-06-03
Phase 2/3
NCT07535554 The Investigators Will Evaluate the Diagnostic Performance of [18F]-AlF-FAPI-74 PET/CT in… Universitaire Ziekenhuizen KU Leuven Recruiting 2026-04-17
NCT05654753 The Efficacy of Fecal Microbiota Transplatation on Axial Spondyloarthritis Patients… Assistance Publique - Hôpitaux de Paris Recruiting 2024-04-09
NCT07339566 Efficacy and Safety of Xeligekimab in the Treatment of Non-Radiographic Axial… Lingli Dong Not Yet Recruiting 2026-01-14
Phase 2
NCT07133633 A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis… Merck Sharp & Dohme LLC Recruiting 2026-09-28
See all 130 active Ankylosing Spondylitis trials with filters →

Top sponsors by active trials in this area

Assiut University (6) · Assistance Publique - Hôpitaux de Paris (4) · China-Japan Friendship Hospital (4) · Kirsehir Ahi Evran Universitesi (4) · Novartis Pharmaceuticals (3) · Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. (3) · The Danish Center for Expertise in Rheumatology (3) · Biocad (2) · Bozyaka Training and Research Hospital (2) · CARE ARTHRITIS LTD. (2)

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