Disease landscape

IPF clinical trials

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89 active trials 44 recruiting 8 Phase 3 64 sponsors 12 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-08-12
critical
Primary completion pushed: 2027-11-01 → 2028-11-01
NCT05988463 Dose-Escalation Study of Artesunate Patients With IPF · Joseph C. Wu · Phase 1
2026-08-04
notable
Enrollment reduced: 10 → 9 participants
Trial completed
NCT07036029 NAL ER IPF Respiratory Function and Safety Study · Trevi Therapeutics · Phase 1
2026-08-01
notable
Trial completed
Primary completion pushed: 2025-01 → 2025-03-13
Completion moved earlier: 2026-12 → 2025-08-01
NCT06230822 Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary… · Wuhan Optics Valley Vcanbiopharma Co., Ltd. · Phase 1
2026-08-13
notable
Recruitment opened
NCT07743996 Emotional and Social Experiences of Antifibrotic (AF) Therapy Among Idiopathic Pulmonary… · Boehringer Ingelheim
2026-08-09
notable
Sponsor changed: Second Affiliated Hospital, School of Medicine, Zhejiang University → Second Affiliated Hospital, Zhejiang University, School of Medicine
NCT07329959 CAR-DC for End-Stage IPF · Second Affiliated Hospital, School of Medicine, Zhejiang University · Phase 1
2026-08-18
minor
Trial sites reduced: 111 → 104 locations
NCT06588686 A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic… · Vicore Pharma AB · Phase 2
2026-08-14
minor
Trial sites expanded: 30 → 36 locations
NCT06968845 A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis · Rein Therapeutics · Phase 2
2026-08-11
minor
Trial sites expanded: 3 → 24 locations
NCT07194382 AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02… · Avalyn Pharma Inc. · Phase 2
2026-08-08
minor
Trial sites expanded: 54 → 68 locations
NCT06951217 An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL) · Avalyn Pharma Inc. · Phase 2

Active trials by phase

Early Phase 1
1
Phase 1
8
Phase 1/2
1
Phase 2
25
Phase 2/3
1
Phase 3
7
Not charted: 46 active trials with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

Active trials top 25 of 89

NCT IDTitleSponsorStatusUpdated
Phase 3
NCT07284602 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to… PureTech Recruiting 2026-08-27
NCT07671911 Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine… Trevi Therapeutics Recruiting 2026-07-10
NCT07082842 Confirmatory Clinical Study of HEC585 Tablets in Patients With IPF Sunshine Lake Pharma Co., Ltd. Recruiting 2026-04-21
NCT07464912 A Adaptive Design Clinical Trial to Evaluate the Efficacy and Safety of TDI01 Suspension… Beijing Tide Pharmaceutical Co., Ltd Recruiting 2026-03-11
NCT07719023 A Phase 3 Study of Efficacy and Safety of AK3280 in Patients With Idiopathic Pulmonary… Shanghai Ark Biopharmaceutical Co., Ltd. Not Yet Recruiting 2026-07-22
NCT07687459 Study Evaluation Rentosertib (INS018_055) Administered Orally in Patients With Idiopathic… InSilico Medicine Hong Kong Limited Not Yet Recruiting 2026-07-07
NCT07519070 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate… Haisco Pharmaceutical Group Co., Ltd. Not Yet Recruiting 2026-04-09
Phase 2/3
NCT06125327 SC1011 Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis… Guangzhou JOYO Pharma Co., Ltd Recruiting 2024-11-19
Phase 2
NCT06968845 A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis Rein Therapeutics Recruiting 2026-08-13
NCT06967805 WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF) Mediar Therapeutics Recruiting 2026-08-10
NCT07194382 AURA-IPF: A Randomized Phase 2 Study to Evaluate the Safety and Efficacy of AP02… Avalyn Pharma Inc. Recruiting 2026-08-10
NCT06951217 An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL) Avalyn Pharma Inc. Recruiting 2026-08-07
NCT07036523 A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With… Boehringer Ingelheim Recruiting 2026-07-28
NCT07679893 Phase 2 Clinical Trial of MNKD-201 (Nintedanib Dry Powder Inhalation) in Patients With… Mannkind Corporation Recruiting 2026-07-24
NCT07652658 A Phase IIb Study to Evaluate AZD8965 in Participants With IPF. AstraZeneca Recruiting 2026-06-25
NCT07447102 Phase II Clinical Study of BC006 in Patients With Idiopathic Pulmonary Fibrosis Dragonboat Biopharmaceutical Company Limited Recruiting 2026-05-13
NCT05571059 Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF) Cumberland Pharmaceuticals Recruiting 2026-03-05
NCT07121413 A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and… Shanghai Synvida Biotechnology Co.,Ltd. Recruiting 2026-02-11
NCT07192939 Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Trial to Evaluate the… Guangdong Hengrui Pharmaceutical Co., Ltd Recruiting 2025-12-24
NCT06747923 SB17170 Phase 2 Trial in IPF Patients SPARK Biopharma Recruiting 2025-11-19
NCT05975983 Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary… InSilico Medicine Hong Kong Limited Recruiting 2025-11-12
NCT06588686 A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic… Vicore Pharma AB Active, Not Recruiting 2026-08-17
NCT07728721 Evaluating the Efficacy and Safety of of HSK50042 in People With Idiopathic Pulmonary… Haisco Pharmaceutical Group Co., Ltd. Not Yet Recruiting 2026-07-27
NCT05389215 Clinical Trial to Evaluate the Safety and Efficacy of DWN12088 in Patients With IPF Daewoong Pharmaceutical Co. LTD. Active, Not Recruiting 2026-07-16
NCT05828953 Anlotinib Capsules in the Treatment for IPF/PF-ILDs First Affiliated Hospital of Wenzhou Medical University Active, Not Recruiting 2026-06-05

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