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Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea: A Randomised Comparative Effectiveness Trial

Study acronym: TIRZE-PAP
StatusNot Yet Recruiting
PhasePhase 2/3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study First Submitted
When used, continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), a condition that is mainly caused by overweight and obesity. However, CPAP is plagued by poor adherence and high rates of discontinued use leaving most patients undertreated and at risk of serious health complications. This study aims to test whether new effective weight loss pharmacotherapy is superior to CPAP for alleviating OSA and improving health outcomes.
Trial Details
NCT Number NCT07846865
Lead Sponsor Woolcock Institute of Medical Research
Conditions
(from sponsor)		 Sleep Apnoea, Obesity & Overweight, Sleep Apnea Syndrome, Obstructive
Related terms Obesity, Overweight, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Weight Loss
Enrollment 256 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov