Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery

StatusNot Yet Recruiting
PhasePhase 4
Started

Record status This record was last updated March 18, 2025 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.

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Record History

  1. Study First Submitted
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing minimally invasive colorectal cancer surgery. The investigators expect intrathecal morphine to provide better pain relief at rest 24 hours after surgery, while epidural analgesia may be more effective during movement. By 48 to 72 hours, both methods should offer similar pain control. The epidural group may require fewer additional pain medications but could experience more side effects, including a higher risk of low blood pressure and technical difficulties. Additionally, these patients may have a slightly longer hospital stay. In contrast, the intrathecal morphine group may have fewer overall side effects. Despite these differences, patient satisfaction, sleep quality, and recovery are expected to be similar in both groups. By evaluating these methods, this study aims to determine the most effective and safe approach to post-surgical pain management, improving comfort and recovery outcomes for patients.
Trial Details
NCT Number NCT06881563
Lead Sponsor Meri Mirceta
Conditions
(from sponsor)
Postoperative Pain, Analgesia, Colorectal Cancer, Surgery
Related terms Agnosia, Colorectal Neoplasms, Postoperative Pain
Enrollment 98 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov