Fluid Challenge and Plasma Volume, During Surgery

Study acronym: FC-VE
StatusRecruiting
PhasePhase 4
Started

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Record History

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  1. Primary and study completion dates: Oct 31, 2025 to Oct 31, 2026
    • Eligibility criteria revised
    v3
  2. Trial status: Not Yet Recruiting to Recruiting
    • Primary and study completion dates: Dec 31, 2024 to Oct 31, 2025
    • Start date changed from estimate of Feb 15, 2023 to Oct 23, 2023
    • Study sites: 0 to 1
    v2
  3. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml/kg body weight, albumin 5% 4 ml/kg body weight or albumin 20% 1 ml/kg body weight), using hemoglobin as a dilution indicator.
Trial Details
NCT Number NCT05726136
Lead Sponsor Joachim Zdolsek
Conditions
(from sponsor)		 Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders, Benign Neoplasm
Related terms Colorectal Neoplasms, Neoplasms, Urologic Neoplasms
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov