Regenmedic Cream 2.0 12-week Long-term Clinical Test

The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image analysis and participant self-assessment. The main questions it aims to answer are: Does the test cream produce immediate anti-wrinkle, firming, moisturizing and repairing effects on facial skin after single use? Can 12-week continuous use of the test cream sustainably improve facial skin condition in terms of wrinkles, laxity, hydration and skin repair? This is a single-center clinical study with a self-controlled before-and-after design. Around 70 healthy Chinese women aged 25-50 will be randomly divided into an instrumental group and a questionnaire group, with no fewer than 40 valid clinical test samples and 60 valid questionnaire samples. The study uses four products, including one test cream and three auxiliary skincare products. Participants will: Use the test cream once on-site and continuously at home for 12 weeks with matched auxiliary products. Attend six scheduled visits at key time points: 2 weeks before product use for washout and screening (T-2W), baseline detection and immediate assessment after single product use (T0+Timm), 1 week after continuous product use (T1W), 4 weeks after continuous product use (T4W), 8 weeks after continuous product use (T8W), and 12 weeks after continuous product use (T12W) . Complete group-specific assessments: the instrumental group will undergo instrumental tests, clinical evaluation and image collection; the questionnaire group will finish clinical screening and self-assessment. Receive skin indicator detection and efficacy evaluation at all designated time points to verify the product's skincare effects.