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Co-contraction and Corticoreticular Excitability in Spinal Cord Injury

StatusEnrolling by Invitation
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study First Submitted
This study is to elucidate whether hyperexcitability of the cortico-reticulospinal tract leads to abnormal co-contraction and spasticity of elbow flexors in persons with cervical cervical spinal cord injury. By measuring the supplementary motor area (SMA) regulation of the StartReact response, it is possible to quantify whether the cortico-reticular pathway is excessively active or weakened in these persons. Participants will 1. Be assessed for upper limb function 2. Receive motor evoked potential of tested biceps muscle 3. Receive a standard StartReact paradigm to measure the reticulospinal excitability. 4. Received a conditioning-test paradigm to assess corticoreticular excitability. 5. Conduct a sustained isometric elbow extension task
Trial Details
NCT Number NCT07872839
Lead Sponsor Taipei Veterans General Hospital, Taiwan
Conditions
(from sponsor)		 Spinal Cord Injury, Spasticity
Related terms Muscle Spasticity, Spinal Cord Injuries
Enrollment 20 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov