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Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial

StatusNot Yet Recruiting
PhasePhase 2
Started
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Record History

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  1. Eligibility criteria expanded, about 3 words
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Aging is associated with the development of vascular dysfunction, which increases the risk for cardiovascular disease. This clinical trial will assess if supplementation with the natural compound fisetin can improve vascular endothelial function in older adults. The clinical trial will also assess if any effects of fisetin on endothelial function are associated with reduced cellular senescence. The study will also evaluate safety, tolerability and adherence with fisetin treatment.
Trial Details
NCT Number NCT07871162
Lead Sponsor University of Colorado, Boulder
Collaborators: National Institute on Aging (NIA)
Conditions
(from sponsor)		 Aging, Endothelial Dysfunction, Cellular Senescence
Enrollment 136 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov