Beta-1 Band Functional Connectivity Mediates the Effects of Acute Exercise on Cognitive Flexibility in Older Adults With Cognitive Impairment: A Randomized Controlled Trial

StatusNot Yet Recruiting
PhaseNot applicable
Started

Record status This record was last updated October 2, 2026 (before its estimated October 11, 2026 completion). Its status may not reflect the trial's current state.

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Record History

  1. Study First Submitted
Objective: The effects of different exercise modalities (mind-body, aerobic, and resistance training) on cognitive flexibility and brain functional connectivity in cognitively impaired older adults are unknown, and the mechanistic relationships linking acute exercise, cognitive flexibility, and neural connectivity remain unclear. Methods: A total of 60 older adults with cognitive impairment were recruited and randomly assigned to a Baduanjin group (n = 15), a brisk walking group (n = 15), a resistance band group (n = 15), or a control group (n = 15). Five-minute resting-state electroencephalography signals were collected and cognitive flexibility was assessed before and after the intervention. All exercise interventions were performed at a moderate intensity and lasted 30 minutes.
Trial Details
NCT Number NCT07854444
Lead Sponsor Shanghai University of Sport
Conditions
(from sponsor)		 Cognitive Impairment, Cognitive Flexibility, Brain Functional Connectivity
Related terms Cognitive Dysfunction
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov