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Sex Hormones and Aging

Name: Sex Hormones and Aging — clinical trial record (NCT07848438)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhaseNot applicable

SponsorUniversity of Michigan

Started2026-08-20

View on ClinicalTrials.gov ↗

University of Michigan

367 trials monitored

See 20 trials at risk

This study investigates the influence of sex hormones and exercise on age-related neuromuscular decline in females. Specifically, the research aims to evaluate how hormonal variations impact both age-associated neuromuscular decline and the subsequent adaptations to exercise and resistance training. Age-related declines in neuromuscular function are especially pronounced in females, potentially due to the sharp drop in estradiol after menopause. This project will compare postmenopausal females who have not taken hormonal therapy (HT) to age-matched females taking HT.

Trial Details

NCT Number	NCT07848438
Lead Sponsor	University of Michigan
Conditions	Menopause, Menopausal Hormone Therapy, Aging
Enrollment	120 participants
Start Date	2026-08-20
Primary Completion	2031-08 (estimated)
Study Completion	2031-08 (estimated)
Updated on ClinicalTrials.gov	2026-09-30