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Long-acting Local Vaginal Cuff Anesthesia Following Hysterectomy

Study acronym: LAVA
StatusNot Yet Recruiting
PhasePhase 1/2
Started2026-09-17
View on ClinicalTrials.gov ↗
The purpose of this study is to compare recovery unit and post operation day (POD) 1 pain score in women following elective robotic assisted TLH (RA-TLH) for benign indication with and without local vaginal cuff injection of short acting bupivacaine and long acting Exparel, to evaluate postoperative pain management and control by assessing the amount and frequency of NSAIDS and opioids taken and to assess bleeding, vaginal discharge and or vaginal dehiscence at the postoperative follow up visit.
Trial Details
NCT Number NCT07842159
Lead Sponsor The University of Texas Health Science Center, Houston
Conditions Pain, Postoperative
Enrollment 104 participants
Start Date 2026-09-17
Primary Completion 2028-03-17 (estimated)
Study Completion 2028-09-15 (estimated)
Updated on ClinicalTrials.gov 2026-09-25