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The Efficacy and Safety of Tirofiban Enhanced Antiplatelet Therapy in the Treatment of Ruptured Intracranial Aneurysms With Stent

Study acronym: TEARIAS
StatusNot Yet Recruiting
PhasePhase 3
Started2026-09-01
View on ClinicalTrials.gov ↗
This multicenter prospective randomized controlled study will enroll patients with ruptured intracranial aneurysms receiving stent-assisted coiling across multiple Chinese medical centers. The investigators aim to evaluate the efficacy and safety of tirofiban-enhanced antiplatelet therapy versus conventional dual antiplatelet treatment on the 90-day neurological prognosis and major adverse cerebrovascular events of enrolled subjects.
Trial Details
NCT Number NCT07818083
Lead Sponsor First Affiliated Hospital of Fujian Medical University
Conditions Ruptured Intracranial Aneurysms, Subarachnoid Hemorrhage, Aneurysmal
Enrollment 622 participants
Start Date 2026-09-01
Primary Completion 2028-09-30 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-09-14