Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07814352 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

A Study of SX-682 in Combination With Proton Craniospinal Irradiation (pCSI) in People With Leptomeningeal Disease

Name: A Study of SX-682 in Combination With Proton Craniospinal Irradiation (pCSI) in People With Leptomeningeal Disease — clinical trial record (NCT07814352)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhasePhase 1

SponsorMemorial Sloan Kettering Cancer Center

Started2026-09-04

View on ClinicalTrials.gov ↗

Memorial Sloan Kettering Cancer Center

779 trials monitored

See 100 trials at risk

The researchers are doing this study to find out whether SX-682 in combination with proton craniospinal irradiation (pCSI) is a safe treatment approach for people with melanoma or non-small cell lung cancer (NSCLC) with leptomeningeal disease (LMD). The researchers will also look at whether the treatment combination is effective against participants' cancer.

Trial Details

NCT Number	NCT07814352
Lead Sponsor	Memorial Sloan Kettering Cancer Center Collaborators: National Comprehensive Cancer Network, Syntrix Pharmaceuticals
Conditions	Leptomeningeal Disease (LMD)
Enrollment	40 participants
Start Date	2026-09-04
Primary Completion	2029-09 (estimated)
Study Completion	2029-09 (estimated)
Updated on ClinicalTrials.gov	2026-09-11