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Effects of Acute Exercise in Fasting and Fed States in Individuals With Different Aerobic Fitness Levels

Name: Effects of Acute Exercise in Fasting and Fed States in Individuals With Different Aerobic Fitness Levels — clinical trial record (NCT07813403)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusNot Yet Recruiting

PhaseNot applicable

SponsorHacettepe University

Started2026-11-15

View on ClinicalTrials.gov ↗

Hacettepe University

276 trials monitored

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The aim of this study is to investigate the effects of aerobic fitness level, feeding status, and acute exercise on whole-body metabolic fuel utilization and mitochondrial function in peripheral blood mononuclear cells (PBMCs) in healthy young men. The main questions it aims to answer are: 1. Do individuals with high and low aerobic fitness levels differ in fat and carbohydrate oxidation at rest and during exercise following an overnight fast, and do their PBMC mitochondrial responses to acute exercise differ? 2. Does feeding alter fat and carbohydrate oxidation at rest and during exercise compared with the fasted state in individuals with high aerobic fitness? 3. Are PBMC mitochondrial respiration parameters and their exercise-induced changes associated with fat and carbohydrate oxidation during fasted exercise?

Trial Details

NCT Number	NCT07813403
Lead Sponsor	Hacettepe University
Conditions	Physical Fitness, Mitochondrial Function, Bioenergetics, Mitochondria, Energy Metabolism
Enrollment	30 participants
Start Date	2026-11-15
Primary Completion	2027-11-15 (estimated)
Study Completion	2027-12-15 (estimated)
Updated on ClinicalTrials.gov	2026-09-10