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Naloxone for In-Hospital Cardiac Arrest

Study acronym: naloxone-IHCA
StatusNot Yet Recruiting
PhasePhase 2/3
Started2027-01-01
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146 trials monitored
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The goal of this clinical trial is to learn if the drug naloxone in addition to cardiopulmonary resuscitation improves outcomes of in-hospital cardiac arrets. The main questions it aims to answer are: Does naloxone improve survival after the cardiac arrest? Does naloxone improve functional outcome in survivors of cardiac arrest? Does naloxone improve health related quality of life after the cardiac arrest? How common are adverse reactions to naloxone when administered during cardiopulmonary resuscitation. Researchers will compare naloxone to a placebo (a look-alike substance that contains no drug) to see if naloxone works during cardiac arrest.
Trial Details
NCT Number NCT07806565
Lead Sponsor Region Skane
Collaborators: Lund University, Clinical Studies Sweden - Forum South, Copenhagen Trial Unit, Center for Clinical Intervention Research
Conditions Heart Arrest
Enrollment 850 participants
Start Date 2027-01-01
Primary Completion 2030-01-31 (estimated)
Study Completion 2031-07-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-08