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The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological Complications

StatusNot Yet Recruiting
PhaseNot applicable
Started2026-09-07
View on ClinicalTrials.gov ↗
Postoperative delirium and postoperative ischemic stroke are common neurological complications in clinical practice. The incidence of these complications is further increased in patients undergoing neurosurgical procedures. Intraoperative hypotension and burst suppression are high-risk factors for postoperative delirium and ischemic stroke. Ciprofol, as a new intravenous general anesthetic, can significantly reduce the occurrence of hypotension and decrease burst suppression compared with propofol. However, no study has demonstrated that the application of ciprofol in neurosurgical patients can improve patient prognosis. Therefore, the purpose of this study is to explore the impact of using ciprofol or propofol in anesthesia induction and maintenance on postoperative neurological complications in patients with high intracranial pressure.
Trial Details
NCT Number NCT07805876
Lead Sponsor Beijing Tiantan Hospital
Conditions Intracranial Tumors
Enrollment 434 participants
Start Date 2026-09-07
Primary Completion 2028-09-30 (estimated)
Study Completion 2029-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-09-09