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Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA Study

Study acronym: OPTIMA
StatusNot Yet Recruiting
PhaseNot applicable
Started2026-11-01
View on ClinicalTrials.gov ↗
The goal of this clinical trial is to learn if myopia-control eyeglass lenses (Essilor® Stellest® 2.0) can slow down the progression of short-sightedness (myopia) in young adults, compared with standard single-vision lenses. The main questions it aims to answer are: Does wearing Stellest® 2.0 lenses slow the increase in eye length (axial length) after 1 year, compared with standard lenses? Does wearing Stellest® 2.0 lenses reduce the change in glasses prescription and the occurrence of eye complications after 2 years, compared with standard lenses? How well do participants tolerate the Stellest® 2.0 lenses in the first weeks of wear? Researchers will compare Stellest® 2.0 myopia-control lenses to standard single-vision lenses to see if they reduce the worsening of myopia. Participants will: Wear either the study glasses or standard glasses every day, at least 12 hours a day, for 2 years Attend an eye exam and vision check at the start of the study, after 1 year, and after 2 years Complete three phone check-ins during the first 3 months to report on comfort and how well they tolerate their glasses
Trial Details
NCT Number NCT07804043
Lead Sponsor Fondation Ophtalmologique Adolphe de Rothschild
Conditions Myopia
Enrollment 134 participants
Start Date 2026-11-01
Primary Completion 2028-12-01 (estimated)
Study Completion 2030-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-09-04